

Model called it
The model favored ISU to win, and the call landed.
Iowa State's got this one locked down at ninety-nine percent to win. The Cyclones are facing a massive talent gap here, and Vegas has them favored by thirty and a half points, which really tells you everything you need to know about the matchup. Southeast Missouri State's sitting at just one percent, and when you look at the Elo ratings and Iowa State's strong form over their last five games, it's hard to see any path to an upset today.
Model vcfb-1.0.0 · predicted Sep 5, 2026 · not betting advice